THE SCIENCE
Explainer: What the Evidence Really Says About GLP-1 Drugs in Type 1 Diabetes
Searches for "Mounjaro type 1 diabetes" keep returning a question the clinical record has not fully answered. Type 1 diabetes is an autoimmune disease in which the body's insulin-producing...
THE SCIENCE
Corn Smut Hides a Peptide Inside a Protein. The Plant’s Own Enzymes Hand It Over
Corn smut is the fungus that turns maize kernels into grey, swollen galls. In Mexico, young galls are harvested as huitlacoche and sold as...
THE SCIENCE
Trevogrumab Preserved Lean Mass on Semaglutide. The Combination Arm Is the Warning
Trevogrumab, an experimental antibody from Regeneron, substantially reduced the lean tissue people lost while taking semaglutide, according to the full results of the COURAGE...
THE SCIENCE
Mountain Bumble Bees Carry Different Venom. Raised in a Lab, the Difference Faded
Anyone who has felt a bumble bee sting knows the venom works. What almost nobody asks is whether it is the same venom everywhere.
A...
THE SCIENCE
GLP-1 Drugs Were Linked to Fewer Obesity-Related Cancers Than Insulin. Against Newer Drugs, the Gap Vanished
The question of GLP-1 and cancer has swung back and forth for two decades, from thyroid tumors in rodents to hopeful headlines about lower...
THE SCIENCE
Lifting Weights on Tirzepatide Cut Lean-Mass Loss by a Quarter. Strength Went Up Instead of Down
Tirzepatide muscle loss has become one of the most frequently discussed questions about the new generation of obesity drugs. Until recently, much of the...
THE SCIENCE
Prolynx Wants an Obesity Shot You Take Four Times a Year. So Far It Has Worked in Rats
The best-selling obesity medicines are weekly injections. Drugmakers are now working to stretch treatment intervals to once a month. Prolynx, a venture-backed biotechnology company...
THE SCIENCE
Merck’s Liver Peptide Cleared MASH in 6 of 10 Patients. Its Highest Dose Stumbled on Scarring
By Grey Pepper Editorial
Merck has spent years developing a liver-disease strategy around an unusual idea: combine GLP-1 receptor activation with glucagon receptor activation in...
THE SCIENCE
Cows That Make Better Milk From Their Feed Carry More of One Tiny Dipeptide in Their Gut
A dairy cow eats a lot of protein and turns surprisingly little of its nitrogen into milk.
Depending on the animal, somewhere between about 14%...
THE SCIENCE
Survodutide Heart Safety Trial: What the Lancet Data Show
Every new obesity drug eventually has to answer a question that has nothing to do with the bathroom scale: does it increase the risk...
THE SCIENCE
GSK’s Monthly Liver Shot Softened Scarred Livers in 39 People. Nobody Got a Placebo
Most of the excitement in fatty liver disease this year has belonged to GLP-1 drugs. A different hormone is quietly building its own case.
At...
