PEPTIDES
Blackstone Will Pay Up to $1.5 Billion of Berobenatide’s Bills. Pfizer Keeps the Whole Drug
Pfizer has found someone else to help pay for its biggest obesity bet. On November 11, Pfizer and Blackstone Life Sciences said funds managed by Blackstone will cover up...
PEPTIDES
Ozempic Starts in Yeast. Zepbound Is Built by Chemists. Inside the Two Ways GLP-1 Peptides Get Made
Every GLP-1 injection starts as a manufacturing decision. A peptide drug is a chain of amino acids, and there are two major ways to...
PEPTIDES
Ascletis Wants GLP-1 and Amylin in One Daily Pill. The Combination Has Only Been Tested in Dogs
The obesity field's favorite pairing has been an injection: a GLP-1 drug plus an amylin drug, the logic behind Novo Nordisk's investigational CagriSema and...
PEPTIDES
MBX Biosciences Has $482 Million and a Stack of Monthly Obesity Peptides. The First Human Data Are Weeks Away
MBX Biosciences is the kind of company whose quarterly report reads like two businesses sharing an office.
One half is a late-stage program for a...
PEPTIDES
Your proposed headline says DA-1726 reduced weight by 13.5% in 15 participants. That is not quite right.
MetaVia is preparing to compare its experimental obesity drug with one of the most closely watched molecules in the field: Eli Lilly's retatrutide.
At ObesityWeek...
PEPTIDES
Medicare Drug Price Negotiation Gets a Permanent Rulebook. The Combo-Drug Loophole Is Narrower Than It Sounds
The Medicare Drug Price Negotiation Program has acquired something it did not previously have: a permanent regulatory framework governing its operations from 2029 onward.
On...
PEPTIDES
A Monthly Shot Held Off Weight Regain After a Year on Bofanglutide. The Data Are Still a Press Release
The most uncomfortable fact about modern obesity drugs is what happens when treatment stops. People often regain a substantial share of the weight they...
PEPTIDES
Wegovy Lowered Liver Markers in Fatty-Liver Patients Who Weren’t Obese. The Group Was 106 People.
Most of the story told about Wegovy and fatty liver disease runs through weight. The medicine helps people lose a substantial amount of it,...
PEPTIDES
America’s First Hepatitis D Drug Is a 47-Amino-Acid Peptide. The Harder Problem Is Finding Patients.
Hepcludex, Gilead's brand of bulevirtide, is one of the more unusual peptide drugs to reach the American market.
It is a synthetic 47-amino-acid lipopeptide designed...
PEPTIDES
Adding Zepbound to Taltz Nearly Tripled Arthritis Responses at a Year. Read the Fine Print First
Taltz and Zepbound are about to share a podium again.
On Wednesday, November 11, Eli Lilly will present detailed 52-week results from TOGETHER-PsA, a Phase...
PEPTIDES
Entera Wants to Turn a Daily Bone-Building Shot Into a Pill. It Has the Cash, Not Yet the Proof.
Oral teriparatide has been one of pharmaceutical drug delivery's stubborn ambitions: take a peptide hormone that builds bone, a molecule normally injected under the...
